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\begin{abstract} |
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|
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I present a dissertation concerning the structural properties and |
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phase behavior of lipid bilayers. At first, I investigated the system |
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< |
by using Monte Carlo simulations on a simple dipolar membrane |
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< |
model. Secondly, to obtain the dynamical properties of the ripple |
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< |
phase of lipid membranes, molecular dynamics simulations were |
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performed on a more realistic molecular-scale lipid model. Finally, an |
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< |
algorithm of Langevin dynamics was developed to investigate the ripple |
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phase in an implicit solvent environment. |
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> |
phase behavior of lipid bilayers. The $P_{\beta'}$ ripple phase, |
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> |
named for the periodic buckling of the membrane, is an thermotropic |
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> |
phase which develops either from heating the gel phase ($L_{\beta'}$) |
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> |
or cooling the fluid phase ($L_\alpha$). This phase typically exhibits |
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surface buckling with wavelengths of $100-250$ \AA~and amplitudes of |
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> |
$10-50$ \AA. At first, I investigated the system by using Monte Carlo |
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> |
simulations on a simple dipolar membrane model. Secondly, to obtain |
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> |
the dynamical properties of the ripple phase of lipid membranes, |
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> |
molecular dynamics simulations were performed on a more realistic |
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> |
molecular-scale lipid model. Finally, an algorithm of Langevin |
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> |
dynamics was developed to investigate the ripple phase in an implicit |
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> |
solvent environment. |
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|
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\end{abstract} |
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|
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Christie Puglis, Patrick Holvey, Matthew A.~Meineke, Christopher |
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J.~Fennell, Yang Zheng, Kyle Daily, Kyle S.~Haygarth, Jennifer Morton, |
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|
who were always here for technical support and helpful suggestions. I |
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< |
would also like to thank the members in my advisory commitee, Dennis |
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< |
C.~Jacobs, Gregory V.~Hartland, and S.~Alex Kandel for their |
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disscusion and review of my dissertation. I would also like to thank |
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Dr.~Steven Corcelli for the useful comments. Finally, I would like to |
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thank my family: my father, Jianguo Sun, and my mother, Yumei Lin, for |
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their understanding and support on the distant side of the world. And |
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< |
my wife, Yingxin, this dissertation could not have been finished |
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< |
without her love. |
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> |
would also like to thank the members in my advisory commitee, Gregory |
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> |
V.~Hartland, S.~Alex Kandel, Steven Corcelli, and Dennis C.~Jacobs for |
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> |
their disscusion and review of my dissertation. Finally, I would like |
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> |
to thank my family: my father, Jianguo Sun, and my mother, Yumei Lin, |
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> |
for their understanding and support on the distant side of the |
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> |
world. And my wife, Yingxin, this dissertation could not have been |
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> |
finished without her love. |
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|
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\end{acknowledge} |
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|
