14 |
|
\begin{figure} |
15 |
|
\centering |
16 |
|
\includegraphics[width=\linewidth]{./figures/inLipid.pdf} |
17 |
< |
\caption{The chemical structure of glycerophospholipids (left) and |
18 |
< |
sphingophospholipids (right).\cite{Cevc80}} |
17 |
> |
\caption[The chemical structure of lipids]{The chemical structure of |
18 |
> |
glycerophospholipids (left) and sphingophospholipids |
19 |
> |
(right).\cite{Cevc80}} |
20 |
|
\label{Infig:lipid} |
21 |
|
\end{figure} |
22 |
|
Glycerophospholipids are the dominant phospholipids in biological |
31 |
|
\begin{table*} |
32 |
|
\begin{minipage}{\linewidth} |
33 |
|
\begin{center} |
34 |
< |
\caption{A number types of phosphatidycholine.} |
34 |
> |
\caption{A NUMBER TYPES OF PHOSPHATIDYCHOLINE} |
35 |
|
\begin{tabular}{lll} |
36 |
|
\hline |
37 |
|
& Fatty acid & Generic Name \\ |
46 |
|
\end{center} |
47 |
|
\end{minipage} |
48 |
|
\end{table*} |
49 |
< |
When dispersed in water, lipids self assemble into a mumber of |
49 |
> |
When dispersed in water, lipids self assemble into a number of |
50 |
|
topologically distinct bilayer structures. The phase behavior of lipid |
51 |
|
bilayers has been explored experimentally~\cite{Cevc80}, however, a |
52 |
|
complete understanding of the mechanism and driving forces behind the |
61 |
|
\begin{figure} |
62 |
|
\centering |
63 |
|
\includegraphics[width=\linewidth]{./figures/inPhaseDiagram.pdf} |
64 |
< |
\caption{Phases of PC lipid bilayers. With increasing |
65 |
< |
temperature, phosphotidylcholine (PC) bilayers can go through |
66 |
< |
$L_{\beta'} \rightarrow P_{\beta'}$ (gel $\rightarrow$ ripple) and |
67 |
< |
$P_{\beta'} \rightarrow L_\alpha$ (ripple $\rightarrow$ fluid) phase |
68 |
< |
transitions.~\cite{Cevc80}} |
64 |
> |
\caption[Phases of PC lipid bilayers]{Phases of PC lipid |
65 |
> |
bilayers. With increasing temperature, phosphotidylcholine (PC) |
66 |
> |
bilayers can go through $L_{\beta'} \rightarrow P_{\beta'}$ (gel |
67 |
> |
$\rightarrow$ ripple) and $P_{\beta'} \rightarrow L_\alpha$ (ripple |
68 |
> |
$\rightarrow$ fluid) phase transitions.~\cite{Cevc80}} |
69 |
|
\label{Infig:phaseDiagram} |
70 |
|
\end{figure} |
71 |
|
Most structural information about the ripple phase has been obtained |
80 |
|
\begin{figure} |
81 |
|
\centering |
82 |
|
\includegraphics[width=\linewidth]{./figures/inRipple.pdf} |
83 |
< |
\caption{Experimental observations of the riple phase. The top image |
84 |
< |
is an electrostatic density map obtained by Sun {\it et al.} using |
85 |
< |
X-ray diffraction~\cite{Sun96}. The lower figures are the surface |
86 |
< |
topology of various ripple domains in bilayers supported in mica. The |
87 |
< |
AFM images were observed by Kaasgaard {\it et |
88 |
< |
al.}.~\cite{Kaasgaard03}} |
83 |
> |
\caption[Experimental observations of the riple phase]{Experimental |
84 |
> |
observations of the riple phase. The top image is an electrostatic |
85 |
> |
density map obtained by Sun {\it et al.} using X-ray |
86 |
> |
diffraction~\cite{Sun96}. The lower figures are the surface topology |
87 |
> |
of various ripple domains in bilayers supported in mica. The AFM |
88 |
> |
images were observed by Kaasgaard {\it et al.}.~\cite{Kaasgaard03}} |
89 |
|
\label{Infig:ripple} |
90 |
|
\end{figure} |
91 |
|
Figure~\ref{Infig:ripple} shows the ripple phase oberved by both X-ray |
98 |
|
physical mechanism for the formation of the ripple phase has never |
99 |
|
been explained and the microscopic structure of the ripple phase has |
100 |
|
never been elucidated by experiments. Computational simulation is a |
101 |
< |
perfect tool to study the microscopic properties for a |
101 |
> |
very good tool to study the microscopic properties for a |
102 |
|
system. However, the large length scale of the ripple structures and |
103 |
|
the long time required for the formation of the ripples are crucial |
104 |
|
obstacles to performing the actual work. The principal ideas explored |
137 |
|
\begin{figure} |
138 |
|
\centering |
139 |
|
\includegraphics[width=3in]{./figures/inFrustration.pdf} |
140 |
< |
\caption{Frustration on triangular lattice, the spins and dipoles are |
141 |
< |
represented by arrows. The multiple local minima of energy states |
142 |
< |
induce frustration for spins and dipoles resulting in disordered |
143 |
< |
low-temperature phases.} |
140 |
> |
\caption[Frustration on triangular lattice]{Frustration on triangular |
141 |
> |
lattice, the spins and dipoles are represented by arrows. The multiple |
142 |
> |
local minima of energy states induce frustration for spins and dipoles |
143 |
> |
resulting in disordered low-temperature phases.} |
144 |
|
\label{Infig:frustration} |
145 |
|
\end{figure} |
146 |
|
The spins in figure~\ref{Infig:frustration} illustrate frustration for |