| 154 |
|
scale biological systems, such as membrane phase behavior, a specific |
| 155 |
|
interest within our group. |
| 156 |
|
|
| 157 |
+ |
One of the key limitations of this water model, however, is that it |
| 158 |
+ |
has been parameterized for use with the Ewald Sum technique for the |
| 159 |
+ |
handling of long-ranged interactions. When studying very large |
| 160 |
+ |
systems, the Ewald summation and even particle-mesh Ewald become |
| 161 |
+ |
computational burdens with their respective ideal $N^\frac{3}{2}$ and |
| 162 |
+ |
$N\log N$ calculation scaling orders for $N$ particles.\cite{Darden99} |
| 163 |
+ |
|
| 164 |
|
Up to this point, a detailed look at the model's structure and ion |
| 165 |
|
solvation abilities has been performed.\cite{Ichiye96} In addition, a |
| 166 |
|
thorough investigation of the dynamic properties of SSD was performed |
