mattDisertation/collections/lipidIntro.tex



\section{\label{sec:lipidIntro}Introduction}

The main focus in this research has been the development of a model
for phospholipid simulations, specifically one capable of forming
lipid bilayers. in the past, researchers have approached this problem
from two different approaches. The first, is complete specification of
a factual phospholipid, an all-atom model. All-atom models have been
used with success in systems of ({\color{red} LIST OF
CITATIONS}). These simulations have been limited in their size and
time scales due to the amount od information calculated at every
integration step. Typically these simulations have $\sim64$~lipids
with roughly 25~waters for every
lipid\cite{saiz02,lindahl00,venable00,Marrink01}. This means there are
on the order of 8,000 atoms needed to simulate these systems. The
amount of calculation required limits the length of time all-atom
simulations may run. Processor power is continually increasing, however, these simulations typically run for times up to 10~ns.{\color{red}CITE ME}

A second popular approach is to the phospholipid
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2
3			\section{\label{sec:lipidIntro}Introduction}
4
5			The main focus in this research has been the development of a model
6			for phospholipid simulations, specifically one capable of forming
7			lipid bilayers. in the past, researchers have approached this problem
8			from two different approaches. The first, is complete specification of
9			a factual phospholipid, an all-atom model. All-atom models have been
10	mmeineke	766	used with success in systems of ({\color{red} LIST OF
11			CITATIONS}). These simulations have been limited in their size and
12			time scales due to the amount od information calculated at every
13			integration step. Typically these simulations have $\sim64$~lipids
14			with roughly 25~waters for every
15			lipid\cite{saiz02,lindahl00,venable00,Marrink01}. This means there are
16			on the order of 8,000 atoms needed to simulate these systems. The
17			amount of calculation required limits the length of time all-atom
18			simulations may run. Processor power is continually increasing, however, these simulations typically run for times up to 10~ns.{\color{red}CITE ME}
19
20			A second popular approach is to the phospholipid